NMR Testing Laboratory

Industrial NMR Spectroscopy Applications

You are here: Home / Archives for Process NMR

MestreLab MNova Users Meeting – SMASH 2013 – PNA NMR Presentation

by Chemistry, Chemometrics, Herbal Supplement, NMR, Process NMR, qNMR, Reaction Monitoring

“Utilization of MNova in a Commercial NMR Testing Laboratory for: 1) Development of Automated Quantitative Analysis Methods by Direct Internal Standard NMR Measurements, and 2) Pre-Processing of Large NMR Datasets for Chemometric Regression Analyses to Derive Chemical and Physical Properties” – presented by John Edwards at the MNova Users Meeting – SMASH 2013 – Santiago de Compostela, Spain, September 22, 2013
PDF of Presentation

Automated 1H qNMR analysis of complex mixtures – example of aloe vera powder 200x

Final automated analysis output for aloe vera analysis – assignments and quantitative output.

Chemometric analysis – spectrum processing and X-matrix preparation performed in MNova – ascii output imported into Eigenvector Research Solo for PLS regression or PCA analysis. Correlation of 1H NMR at 300 or 60 MHz with GC analysis of EPA and DHA content (wt%).

 

NMR Studies of Spontaneously Fermented Sour Beers

by NMR, Process NMR, Reaction Monitoring

At the recent ACS NERM 2013 meeting Adam Dicaprio of Process NMR Associates presented two topics on sour beer analysis by NMR.

“Small Molecule Chemistry of Spontaneously Fermented Coolship Ales” … PDF Technical Poster

“When Beer Goes Sour: An NMR Investigation” … PDF – Oral Presentation

NMR Assignments of interest. 1H qNMR obtained from relative molar ratios established from compaison of maleic acid internal standard with small molecule signals.

Comparison of 60 and 300 MHz 1H NMR Data – Prediction Models for EPA and DHA Omega-3 Fatty Acid Content

by Herbal Supplement, NMR, PAT, Process NMR, Reaction Monitoring

At the recent ACS NERM 2013 meeting in New Haven CT, John Edwards gave a talk on the comparison of 60 and 300 MHz 1H NMR based predictive models for EPA and DHA omega-3 fatty acid content in a fish oil manufacturing process. The presentation can be found here…..

PDF Presentation

Note – spectra are read into the chemometrics software backwards …

2nd Annual Practical Applications of NMR in Industry Conference (PANIC) Announced

by ESR, NMR, Process NMR, Reaction Monitoring, TD-NMR

Conference Details: 2nd Annual Practical Applications of NMR in Industry Conference
Organized by Cambridge Healthtech Institute
Hilton Charlotte University Place, Charlotte, NC, February 3-5, 2014

Building on the success of last years 1st Annual PANIC NMR Conference it has been decided that the 2nd Annual PANIC NMR Conference would be organized cooperatively between the original organizing committee and CHI.

Details on the conference can be found at: PANIC Conference Website

A promotional flyer for the conference can be found here: PANIC NMR Flyer

Anyone interested in industrial applications of all forms of NMR spectroscopy is encouraged to attend this practical NMR conference where the emphasis is placed on everyday utilization of the technology rather than cutting edge NMR research which is often far beyond the capabilities of the everyday user.

John Edwards of Process NMR Associates is serving on the organizing committee and chairing two technical sessions – one on On-Line/At-Line/Benchtop NMR and another on NMR of Materials.

If you are interested in presenting or sponsoring the conference please contact CHI through the website.

Process NMR Associates and Pfizer Present Joint Poster on Reaction Monitoring at PittCon

by NMR, PAT, Process NMR, Reaction Monitoring

Pfizer has included the Aspect-60 MHz NMR system in their reaction monitoring investigations. The analysis was performed on reactions that were monitored in parallel by a Bruker 400 MHz NMR system. The poster of the initial results will be presented by Dr David Foley of Pfizer at this weeks PittCon in Philadelphia.

The presentation is available here.