Process NMR Associates Present Crude Analysis Presentation at Crude Oil Quality Group Meeting
Presented on June 18, 2009
Philadelphia, PA
“Spectroscopy Based Crude Assays for Laboratory, At-Line, and On-Line Applications”
This Presentation can be found at the Crude Oil Quality Group Website (http://www.coqa-inc.org/061809Giammatteo.pdf)
A Self-Employed Application Chemists Odyssey in the World of Analytical Instrument Development: The Viability of a $50K High Resolution NMR and $15K ESR Spectrometers
Presented at Marist College, Poughkeepsie
September 23, 2009
A Self-Employed Application Chemists Odyssey in the World of Analytical Instrument Development The Viability of a $50K High Resolution NMR and $15K ESR Spectrometers
By John C. Edwards, Ph.D.
Process NMR Associates, LLC, Danbury CT
The availability of cheap commodity electronics developed for the cellular phone industry is revolutionizing the design of NMR and ESR spectrometers. Rather than instruments that fill half a room, cost $200-3,000K+, and intimidate users, it is possible to produce spectrometers that are an order of magnitude cheaper to produce. Examples of NMR and ESR spectrometer development projects will be described as well as the wide-ranging applications that these spectrometers can deliver to the areas or process control, food authentification and automated laboratory analysis.
Bio:
John Edwards was born and raised in Bolton, UK. He graduated from the University of Durham, UK with a B.Sc. in Chemistry in 1986. He obtained his Ph.D. in Physical Chemistry from the University of South Carolina in 1990, working on solid-state NMR applied to heterogeneous catalysts under the guidance of Professor Paul Ellis. From 1990-1997 he worked as a research chemist at the Texaco R&D facilityin Beacon, NY where he was responsible for global NMR support of upstream, downstream, and petrochemical Texaco ventures. In 1997 he formed Process NMR Associates which operates as a commercial analytical NMR spectroscopy service and consultancy. Process NMR Associates along with its engineering company partners, develops, markets, and supports on-line process NMR spectrometers utilized for control and optimization of refinery, petrochemical, pharmaceutical and food manufacturing operations. The company also acts as an application development company for several analytical instrument companies and supports the chemometric development of several process analytical products. He currently resides in Poughkeepsie, NY, with his wife and 3 sons. He is an affiliate professor of Chemistry at Marist College, a Research Associate at SUNY New Paltz, and an active member of the American Chemical Society.
A copy of the presentation can be provided on request… contact John Edwards if interested.
News: Process NMR Associates and TopNIR Sign Partnership Agreement
Topnir Systems is proud to announce the signature in October 2009 of a Partnership Agreement with Process NMR Associates, LLC.
This partnership enables Process NMR to utilize our field proven software in complementary fields NMR and MIR combining forces to deliver total solutions with increased added value to customers.
Topnir Systems is a French company leader in the field of online Near InfraRed (NIR) analyzers. Topnir enables measuring and monitoring multiple hydrocarbon streams in less than one minute using a single online system. The company has a long history in the refining and petrochemicals business, being the first world wide to implement an online application designed to measure and control octane number for gasoline production, first NIR on-line application worldwide on Ethylene Plant Naphtha feed (1986), Gasoline (1989) and Crude (1991). The business started in the late 80s within BP Oil, with applications development around gasoline and diesel blending, as well as FCC, CDU, Reformer and Ethylene plant feed andproducts characterization. Major oil companies such as Shell, BP, Repsol, Aramco… have adopted Topnir solutions.
Topnir has recently expanded its activities to provide platform independent software for NIR systems already installed in the field. Topnirs modeling technology offers a full set of properties from a single model which offers the advantage of a robust, reliable system requiring very light maintenance. In addition Topnir is field proven to have ASTM and better results.
Process NMR Associates, LLC is an American company and leader in the field of online Nuclear Magnetic Resonance (NMR) process applications. The company also has a long history in the refining and petrochemicals business, being the first world wide to implement online NMR applications for gasoline and diesel blending, FCC, CDU, Reformer and Ethylene plant feed and products characterization.
Topnir Systems
425, rue RenéDescartes
Espace Descartes, Bat C
Parc de la Duranne
13857 Aix-en-Provence, France
Tel +3350 73 47 / Fax+3350 73 50
Web: www.topnir..com
USA Contact: Julie Williams Tel: +1-508-736-2696
Process NMR Associates, LLC
87A Sand Pit Road
Danbury, Connecticut 06810 USA
Tel +203-744-5905
Fax +203-743-9297
Web: www.process-nmr.com
Contact: Dr. Paul Giammatteo
PNA Presentations at 104th Gulf Coast Conference
Paul Giammatteo recently presented two papers at the Gulf Coast conference that was held in Galveston, Texas on January 20-21.
His first paper was entitled “Counting Carbons for Tighter Control: Combining GC and NMR to Improve Distillate Manufacturing” and centers on the topics of Simulated distillation correlated to 1H NMR.
The second paper was entitled “Analytical Data For Engineering Support: Improving the Lab/Process Interface”. This paper details the development of a series of heavy petroleum applications on a Smiths Detection FTIR-ATR spectrometer.
PDFs of the presentations can be obtained from the following links: 1) NMR Talk 2) FTIR-ATR Talk
ASTM F2259-03 (2008) – Determining the Chemical Composition and Sequence in Alginate by 1H NMR
Alginate is a linear polysaccharide composed of mannuronate (M) and a-L-guluronate (G). The polysaccharide is characterized by the relative ratio of M/G, G-Content, and average length of blocks of G in the polymer. M and G are:
ASTM F2259 recounts the standard sample preparation and 1H NMR analysis that allows the following parameters to be calculated:
The 1H Spectra obtained on a typical alginate sample are show below:
Finally the peaks representing the individual M and G components and sequences are deconvoluted from the spectrum.
The intensities obtained from the deconvolution are input into the excel spreadsheet shown above and the various ratios, M and G content and a series of diads and triads are calculated along with some G block lkength information. It is the block length information that often reveals telling differences between samples.
Process NMR Associates performs this analysis at a cost of $225 per sample. The samples, however, must be prepared by the customer using the methodologt set forth in the test method.
NMR Analysis of Vinegar for Authentification and Detection of Adulteration
Over the past few years balsamic vinegars have been the subject of a number or NMR studies to determine authenticity, degree of aduleration, and age. 1H NMR has been used to quantify the relative concentrations of a series of organic components (ethanol, fructose, glucose, acetic acid, succinic acid, lactic acid, butandiol, etc (ref 1). 13C NMR has been used to determine the aunthenticity and degree of adulteration (ref 2) as well as the length of the ageing process that a given sample has undergone. Also the formation of glucose and fructose acetates during maturation and ageing has been studied by 1H and 13C NMR.
Refs.
1) Caligiani et al., Anal. Chim. Acta, 585 (2007) 110-119
2) Consonni et al., Talanta, 75 (2008) 765-769
3) Consonni et al., Anal. Chim. Acta, 611 (2008) 31-40
4) Consonni and Caligiani, Talanta, 73 (2007) 332-339
5) Cirlini et al, Food Chemistry, 112 (2009) 51-56
The concentration and distribution of the organic components has been found to correlate well with ageing process analysis, identification of adulteration, and determination of authenticity of traditional balsamic vinegars and balsamic vinegars of Modena.
Below are a series of spectra showing what can chemistry can be quantified in the balsamic vinegars as well as a few comparative spectra of apple cider vinegar and malt vinegar.
NMR Analysis of Commercial Pear Cider
For comparison with the home made ciders analyzed in the previous posting I am including the NMR of analysis of a commercial pear cider. The previous ciders were very dry while the pear cider was decidedly sweet. The carbohydrate content is a notable difference. The 1H spectrum is shown with chemical components identified.
1H NMR Analysis of Hard Apple Cider
There have been quite a lot of NMR studies centered around apple cider (non-alcoholic) and apple cider vinegar. However a search of the literature turns up no reference for NMR analysis of hard apple cider. This effort was undertaken to analyse the alcohol content of the ciders and to determine the malic and acetic acid content. Ciders were produced by Dr Tim McMahon of Orange Community College, NY….for his own consumption.
Below are the NMR spectra obtained by regular 1H acquisition and with BINOM solvent suppression.
Data was obtained on our Varian 300 MHz spectrometer. Samples were prepared by degassing followed by addition of 1 drop of D2O as lock solvent.
Micro-ESR Spectrometry of Crude Oils
Process NMR Associates, LLC (Danbury CT) and Active Spectrum, Inc (San Carlos CA) are collaborating in the application of micro-ESR technology to petroleum applications. The initial work has focussed on crude oils but will soon be expanded to residues and cracker feedstocks.
Five samples of crude oil were tested by Micro-ESR spectrometry. The samples were:
1. Vasconia, Magdalena Basin, Columbia (V=39 ppm)
2. Merey, Eastern Venezuela Basin, Venezuela (V=303 ppm)
3. Oriente, Oriente Basin, Ecuador (V=65 ppm)
4. Qua Iboe, Agbada Formation, Niger Delta (V=2 ppm)
5. Basrah Light, Zubair Zone, Iraq (V=29 ppm)
The following spectra were observed:
Figure 1: Micro-ESR Spectra of Crude Oil
The central peak is a combination of a persistent carbon-centered organic radical (g = 2.003) found in asphaltenes, and a vanadyl (VO2+) peak. The additional smaller peaks are associated with vanadyl only.
For producers, the technique could be used to rapidly measure asphaltene concentration on-line. The spin density of the organic radical is a function of the maturity of the oil and will of course vary between deposits. Notwithstanding, rapid electronic measurement of asphaltenes remains a topic of great interest. Similar techniques have also been used to assess the quality of coals. For refiners, vanadium is a contaminant that poisons the refinery catalyst. ESR has been used by refiners since 1962 to rapidly measure vanadium content in crude oil feedstocks both on-line and in laboratories. Active Spectrum Inc.’s Micro-ESR is shown below. It is 2.25″ in diameter by 2.5″ high. Power input is 12-30VDC, and the data interface is USB. The device is available as either an on-line sensor or as a benchtop unit.
Figure 2: Micro-ESR Sensor
Figure 3: Higher Homogeneity Spectrum of Merey Crude
Micro-ESR is complimentary to NMR in that it observes paramagnetic metals and organic radicals which are unobservable by NMR. The stable free radical signal is indicative and quantitative to the amount of asphaltenes in the crude oil sample and vanadium metal content is an important processing parameter for cracking processes as it is active in the passivation of catalysts. NMR on the other hand observed the detailed hydrocarbon chemistry of the sample and yields chemico-physical parameters such as aromaticity, paraffinicity, naphthenicity, distillation, density, PAH distribution. In combination these two technologies yield a detailed picture of the petroleum materials before and during the refining process.
Samples provided by John Edwards of Process NMR Associates, LLC. Micro-ESR analysis provided by James White of Active Spectrum, Inc,
Active Spectrum, Inc. 110 Glenn Way #15, San Carlos, CA 94070 650-610-0720 | 626-628-1970 f | activespectrum.com
Process NMR Associates, LLC. 87A Sand Pit Rd, Danbury, CT 06810 203-744-5905 | 203-743-9297 f | process-nmr.com
PDF Version of Application Note
For more information contact John Edwards (203) 744-5905
Residual Catalytic Cracking (RCC) – Feedstream Analysis by NMR
Current Technique for Feedstream Analysis:
Analysis Performed – Refractive Index, Distillation, Specific Gravity
Calculation Obtained – Watson K-Factor
Outcome: aromatic carbon number, aromatic hydrogen number, total hydrogen content
Proposition: Detailed hydrocarbon analysis for kinetic model development.
Our experience is that an improved and useful analysis can be obtained from NMR
analysis. There are several ways to approach the NMR analysis and the
chemometric approach to correlating NMR data to physico-chemical parameters of
use to process control.
RCC Feedstream Analysis by 1H and 13C NMR: Multivariate Prediction of Chemical and Physical Properties
Presented at the 236th ACS National Meeting, Philadelphia PA, August 17-21, 2008
John C. Edwards Ph.D.
Process NMR Associates LLC
87A Sand Pit Rd, Danbury, CT 06810
Jincheol Kim,
SK Energy Co., Ltd, SK Energy Technology Center,
140-1, Wonchon-dong, Yuseong-gu, Daejeon 305-712, Korea
Summary of Slides
1) 60 MHz process NMR data available from online NMR unit.
2) 300 MHz 1H NMR data available from standard NMR experiments on laboratory NMR system at Process NMR Associates
3) Expansions of 1H NMR data on RCC Feeds
4) Calculated 1H NMR Parameters Represented as an alternative “spectrum” for use in chemometric modeling and linear regression.
5) 13C NMR Data obtained on RCC Feeds
6) Expansions of 13C NMR Data
7) 13C NMR and Average Molecule Parameters Calculated from 13C Spectrum
Calculated 13C NMR Parameters Represented as an alternative “spectrum” for use in chemometric modeling and linear regression.
9) Correlations of Spectra and Calculated Parameters to Physico-Chemical properties of RCC Feeds
10) Correlation of Spectra and Calculated Parameters to Density
11) Variable Selection for Linear Correlation of Calculated NMR Parameters to Physico-Chemical Properties of RCC Feeds.
12) Correlation of Calculated 13C NMR Parameters (C-Type and Average Molecule) with both high resolution 1H and 13C NMR spectra. Models created can be utilized by personnel with no NMR experience to calculate NMR parameters directly from the spectrum without any prior knowledge of integrations or calculations to be performed.
Summary
Chemical and Physical Properties of RCC Feedstreams can be determined
by 1H NMR (at 60 and 300 MHz) and by 13C NMR
H-Type and C-Type Parameters do not provide as good a correlation as is observed
by full spectrum regression. This is due to loss of resolved chemical shift information
when the spectrum is reduced to larger integral areas.
1H NMR can be combined with PLS regression modeling to provide detailed carbon
type analysis for RCC Feeds
Regression analysis of 13C NMR data can be utilized to fully automate the prediction
of 13C NMR type analysis : reducing the necessity for considerable knowledge and
analysis time on the part of the analyst.
For further Detail Contact John Edwards
Diesel Production Control – Combination of NMR and Simulated Distillation to Yield On-Line Carbon Number Distributions
Posted by: processn in NMR, PAT, Process NMR on September 23rd, 2008
Process NMR Associates has developed a database of Simulated Distillation database on a large number of diesel fuels on our Shimadzu 2010-GC with SimDis Software. The analysis is being used to develop distillation prediction models for the process NMR systems as well as explore new avenues of control information that can be derived by combining carbon number distributions obtained from the GC data with the predictive capabilities of online NMR.
For a PDF version of this application article download this: Combination of NMR and Simulated Distillation for Diesel Production Control
Simulated distillation allows carbon number distributions to be calculated and in combination with chemistry observed in the NMR analysis the effect of aromatics and olefins on the paraffin distributios can be estimated. Online NMR predictions can be established that yield real-time carbon number distributions for production control and sulfur species monitoring.
Contact: Paul Giammatteo Tel: +1 (203) 744-5905
Extensive NMR Diesel Database Enhances NMR Model Performance for Unit Control and Product Manufacturing
Posted by: processn in NMR, PAT, Process NMR on September 23rd, 2008
An extensive database (10 years) of diesel samples incorporating all refining processes (distillation through product blending) enables development of robust, wide ranging property predictions independent of crude sources and refinery processing. Consistent attention to data integrity enables expanding model ranges well beyond any typical single unit or process operation. The following slides elucidate the consistency in spectra whether obtained 10 years ago or last week, from within a refinery or on a laboratory spectrometer.
If you are interested in finding out more about NMR and diesel production control contact Paul Giammatteo or phone him at +1 (203) 744-5905 – see the Process NMR Associates website for further information
Quantitative NMR Analysis of Wine – qNMR
Here is an example of a 1H NMR analysis of a 2007 Red Wine submitted for chemical analysis by John W.
If you are interested in wine analysis please contact us.
Solid-State 13C NMR Analysis of Carbonaceous Materials
Over the past 20 years we have obtained the solid-state NMR analysis of pretty much every carbonaceous material that exists – including coal/oil shales/bitumen, polymers/catalysts/fibers, cellulose/polysaccharides/foodstuffs/gels, deposits/dried sewage/meteorites/soils/clays, etc. With the increased attention to coal liquifaction and gasification technologies we have developed an interest in creating an NMR database for coals. Coals were obtained from the Penn State Coal Sample Bank at a very reasonable cost. We have performed CP-MAS, DD-MAS, Variable Contact Time, and T1 inversion recovery experiments on all the samples. We are currently developing regression relationships between the NMR data and the physical and chemical testing data that is provided with the samples. At some point we will write this up as a journal article. Here are some snippets of data from the coal analysis along with a few results obtained on the menagerie of samples we look at on any given day including some oil shales, engine deposits, refinery coke, asphaltenes, and pipe tobacco.
Please inquire if you are interested in the details of the above analyses.
60 MHz TD-NMR System
Process NMR Associates and Spin Resonance Ltd have recently completed the construction a small 60 MHz (1.4T) 5mm TD-NMR system that can be utilized to study T1 and T2 characteristics of novel contrast agents at typical MRI frequencies. Here are a few pictures of the magnet. It is based on N42 neodymium-iron discs (120mm diameter x 30 mm deep).
Process NMR Application: Spectro-Molecular Control for Enhanced Diesel Recovery
Posted by: processn in Energy, NMR, Process NMR on February 28th, 2008
NMR Process Systems – Integrated Solution
Application for Crude Unit and Downstream Processes:
Spectro-Molecular Control for Enhanced Diesel Recovery
NMR Process Systems (NPS) on-line NMR based analytical and process control strategy for enhanced diesel recovery at the crude distillation unit maximizes clean diesel recovery by enabling closer cut point control in the mid-section of the CDU.
Clean Fuels regulations in both the European and American markets have had a substantial impact on a refiners ability to maximize product draws at the refinery front end. Extremely low sulfur requirements for gasoline and diesel have resulted in refiners now being more constrained at the hydro-treaters. Lack of reliable, focused, measurement and control of critical CDU product draws has forced many refiners to significantly undercut these draws in order to ensure minimum error in the final product blends, especially with respect to total sulfur. Depending on a refinery’s crude supply and CDU capacity, a conservative estimate of 300-500+ barrels per day of loss diesel production is typical. With an average of $25-$35 per barrel margin loss, the economic impact of these Clean Fuels Regulations are substantial.
Integrating proven NMR technology with a focused measurement and control strategy enables crude unit operations to cut chemically closer to the hydrotreater constraint limit. The strength of NMR is that it quantitatively and accurately observesthe chemistry of each refinery stream and readily relates that chemistry to chemically dependent parameters such as distillation, cetane, freeze points, etc. The NPS strategy is to cut and control CDU diesel production as closely to the dibenzothiophene distillation limit as possible. Figure 1 illustrates this strategy in terms of both current and proposed NMR based measurements.
Figure 1: Overall NMR measurement and control outline highlighting measurement/control strategies.
Let NMR Process Systems deliver Spectro-Molecular Control to your refinery so that you can achieve real economic and production benefits.
Process NMR Associates – Archives – Gasoline Analysis by NMR and Chemometrics – ENC 1996
Posted by: processn in Chemistry, NIR, NMR, Process NMR on January 28th, 2008
Just came across an old presentation on gasoline analysis by NMR and chemometrics with direct comparisons to Mid-IR and NIR. Presented at the Experimental NMR Conference in March 1996….PDF (3 MB)
Conjugated Diolefins Analysis by COSY NMR
Conjugated diolefins are responsible for fouling of many processes in a refinery. COSY NMR analysis can determine the concentration of these species in many processed petroleum product streams….see PNA webs site.
Schering-Plough Corporation Seeks Process Analytical Technology Manager
Title:
Process Analytical Technology (PAT) Manager
Description:
Implement Process Analytical Technology (PAT) throughout all the Global Quality Sites to identification of incoming materials and monitor manufacturing processes.
Work directly with the sites and Schering Plough Research Institute to help support / initiate the development, validation, and deployment of PAT at the sites.
Review, evaluate, implement, and manage PAT activities.
Provide guidance / technical help to the sites to conduct evaluation and purchase commercial PAT related analytical equipment (e.g. NIR / FT-NIR, Raman / FT-Raman, IR / FT – IR etc.).
Maintain analytical instruments in the lab to comply with cGMP standards and requirements.
Train and mentor laboratory staff on PAT to generate analytical data for routine experiments.
Generate network and infrastructures with various sites of the corporation.
Take full ownership / responsibility and provide effective, meaningful, result driven and pro-active leadership on all PAT projects.
Responsible to transfer knowledge / technology of PAT related projects and activities to sites. Job is located in New Jersey.
Respectfully, Vincent L. Graziano
Recruiting Manager / Global Staffing
Schering-Plough Corporation
556 Morris Avenue, S1-1
Summit, N.J. 07901
Ph: 908-473-2745
Fx: 908-473-2793
Ph: 908-298-5232 (Kenilworth)
Careers: Employment Opportunities
email: vincent.graziano@spcorp.comÂ
NPS – IS : A New Approach to Process Analytical
Press Release – NMR Process Systems – Swagelok Technology Conference, Teaneck NJ - October 23, 2007
NMR Process Systems, LLC Announces : NPS-IS© – NPS Integrated Solutions
NMR Process Systems (NPS) announces a new era in advanced analyzer and process control solutions for on-line and at-line process applications. NPS’s Integrated Solutions (NPS-IS©) approach is designed to take advanced on-line analysis to the next level in delivering real engineering and economic benefit to the user.
NPS-IS©: the first and original source for any and all on-line NMR applications regardless of NMR vendor.
NPS-IS©: the first to offer integrated advanced analytical solutions using multiple technologies in one box.
NPS-IS©: the first to offer a fully integrated Swagelok sampling solution for improved sample switching and reliable measurement.
Too many spectroscopic based on-line analyzer projects (FTIR, NIR, NMR) have failed to meet expectations and/or objectives due to:
·Overselling the measurement
·Underestimating the sampling requirements
·Trying to replace all traditional analyzers with one technique.
NMR Process Systems is positioned to deliver the real benefits of advanced analytical systems in petroleum, petrochemical, chemical, food and beverage and pharmaceutical applications. Moving beyond the traditional replacement analyzer philosophy, NPS-IS© integrating analyzers and advanced controls to deliver real process improvement and economic benefit. Such integration leverages the strength of any individual spectroscopy, shortens per stream analysis time, and builds in internal cross-checking to ensure accuracy.
For more information contact Paul Giammatteo Principal, NMR Process Systems
87A Sand Pit Rd, Danbury, CT 06810 U.S.A. Tel: (203) 744-5905
The RefinIR – FTIR-ATR Petroleum Product Analyzer
Posted by: processn in Chemistry, IR-ATR, Process NMR on October 29th, 2007
Press Release – NMR Process Systems – Gulf Coast Conference, Galveston Island, Texas - October 17, 2007
NMR Process Systems, LLC and Smith’s Detection Launch RefinIRTM – The New Refinery Products Analyzer
In a joint development effort NMR Process Systems and Smith’s Detection have developed a range of petroleum analyzer products based on a mid-infrared spectrometer which utilizes an attenuated total reflection (ATR) sample interface. The ATR allows wipe and swipe sample introduction that is ideal for heavy petroleum analysis. Chemometric approaches to chemical and physical property prediction have been developed as well as analysis by spectral database matching. The FTIR-ATR spectrometer is called the RefinIR which can be utilized in the laboratory for rountine, multi-parameter prediction of petroleum product properties or to aid in process troubleshooting on unusual samples or solid foulants.
For more information contact Paul Giammatteo Principal, NMR Process Systems
87A Sand Pit Rd, Danbury, CT 06810 U.S.A. Tel: (203) 744-5905
Process NMR Associates Develops Oxford QP-20 Spectrometer Replacement
Posted by: processn in NMR, Process NMR on October 29th, 2007
In a joint development effort Process NMR Associates and Resonance Systems Ltd have developed a replacement NMR spectrometer for the Oxford QP-20 TD-NMR analyzer. In many cases the excellent magnet and probe of the QP-20 continue to work effectively long after the NMR spectrometer has died. The Spin Track-20 spectrometer enables the user to completely replace the QP-20 NMR system while retaining the use of the original magnet and probe configuration. The product represents state-of-the-art digital NMR technology allowing newly developed TD-NMR methodologies to be applied to complex systems with all the advantages of a windows computer system (replacing the paper cartridge of the original system). Customers who have malfunctioning QP-20 NMR systems can obtain a modern digital NMR system within 8 weeks of order and for less than $16,000. The modular design of the Spin Track TD-NMR systems allows our engineers to develop replacement systems for all benchtop NMR systems such as those marketed by Oxford Instruments, Bruker Minispec, and Resonance Systems. Contact us if you have a non-functioning system that might be a candidate for the Spin Track upgrade.
For more information contact John Edwards Principal, Process NMR Associates – Spin Track Division
87A Sand Pit Rd, Danbury, CT 06810 U.S.A. Tel: (203) 744-5905
PNA Presentation at 9th Upstate NY NMR Symposium
Posted by: processn in NMR, Process NMR on October 7th, 2007
State University of New York
College of Environmental Science and Forestry (SUNY-ESF)
Syracuse, NY, 13210
Alumni Lounge– Marshall Hall
October 12, 2007
Co-Organizers
| SUNY-ESF | Syracuse University | SUNY Upstate Medical University | Bristol-Myers Squibb |
| Art Stipanovic | Phil Borer | Stewart Loh | Doug Weaver |
| Dave Kiemle | Stephan Wilkens |
Sponsors
- SUNY-ESF
- Syracuse University
- Bruker Biospin
- Bristol-Myers Squibb
- Process NMR Associates LLC
- Isotec
- Cambridge Isotope Laboratories
- Varian Inc.
The 9th annual Upstate NY NMR Symposium will be held at SUNY-ESF on Friday, October 12th featuring keynote speaker Professor Ruth E. Stark, Director Institute for Macromolecular Assemblies, CUNY. Others from around the region will also highlight their work in short presentations and posters.
- Tentative oral presentation program
- Poster session program (posted by 9/12)
There is no cost to attend this symposium due to the generosity of the sponsors listed above but pre-registration is required
Lodging arrangements have not been made for this symposium but a variety of options are available:
The conference will be held in the Alumni Lounge (a.k.a. Nifkin Lounge), Marshall Hall on the SUNY-ESF campus located adjacent to Syracuse University.
Parking has been arranged in the Irving Garage just a short walk from Marshall Hall (campus map).
Tentative Program
| Time | Place | Speaker | Title |
| 8:00-9:10 AM | Alumni Lounge Marshall Hall |
Check-In Coffee + Bagels Poster Setup |
Posters on Display |
| 9:15 | Alumni Lounge | Phil Borer Syracuse University |
Welcome |
| 9:30 | “ | Thomas Szyperski SUNY-Buffalo |
Where do we stand on GFT projection NMR spectroscopy? |
| 9:55 | “ | Yibing Wu SUNY-Buffalo |
GFT-NMR based high throughput structure determination exemplified for NESG targets NeT4 and SR500A |
| 10:10 | “ | Arindam Ghosh SUNY-Buffalo |
NMR structure of NESG target MR32, a member of the family of Trm112p-like proteins |
| 10:25 | “ | Bio-Break | |
| 10:35 | “ | David LeMaster Wadsworth Center – NYS Dept. of Health | Electrostatic stabilization and general base catalysis in the active site of the human protein disulfide isomerasea domain monitored by hydrogen exchange |
| 11:00 | “ | Joseph Hornack RIT |
The relaxivity of Gd-(DTPA-BMA) / Cu+2 mixtures and evidence for a Gd-(DTPA-BMA)-Cu complex. |
| 11:25 | “ | Nelly Aranibar Bristol-Myers Squibb |
Metabolomics in Drug Discovery and development |
| 11:50 | “ | Lunch Poster Session |
|
| 1:30 PM | 140 Baker Lab | Nikolaos Sgourakis Rensselaer Polytechnic Institute |
Pressure Effects on the Ensemble Dynamics of ubiquitin at the Picosecond-to-Nanosecond timescale investigated with isotropic reorientational eigenmode dynamics |
| 1:55 | “ | Paul Giammatteo or John Edwards Process NMR Associates, LLC |
New Developments in Non-traditional NMR Applications |
| 2:25 | “ | George Crull Bristol-Myers Squibb |
Extending Solid State NMR to Address Process Development Issues |
| 2:50 | “ | Gwen Lubey P+G Pharmaceuticals |
Solid State NMR Characterization of Risedronate Hydrate Forms and Dehydrated Risedronate |
| 3:15 | “ | - | Break |
| 3:30 | Keynote Lecture | Prof. Ruth Stark CUNY |
NMR Structural Studies of Protective Plant Biopolymers |
Process NMR Sessions at Eastern Analytical Symposium – November 14
Eastern Analytical Symposium – November 12-15, 2007
Garden State Convention Center, Somerset, New Jersey
Process NMR Technology Sessions
Wednesday, November 14, 2007
Chair: John Edwards, Process NMR Associates
Sponsored by Process NMR Associates
Process NMR Technology I: High-Resolution Studies
9:00 Introduction to NMR in Process Control
John Edwards, Process NMR Associates
9:25 Standardizing and Stabilizing NMR Calibration Transfer
Miko DeLevy, Qualion NMR Analyzers
9:50 More from the Barrel – On-line NMR Increases Diesel Production and Quality
Paul Giammatteo, Process NMR Associates
10:15 Break
10:35 Taking NMR into the Refining Process: Best Practices and Benefits
Marcus Trygstad, Invensys Process Systems
11:00 “Get Your Head Out of the Sand: Use of Reaction NMR to Better Understand Reactions in Process Development”
Andreas Kaerner, Eli Lilly
11:25 Direct Prediction of Gasoline Properties for Monitoring Refinery Processes by H-1 NMR Spectroscopy
Veena Bansal, Indian Oil Company
Process NMR Technology II: Time-Domain Studies
Chair: John Edwards, Process NMR Associates
Sponsored by Process NMR Associates
2:00 “Recent Developments in Time-domain NMR and Its Applications in Polymer Industry”
Harry Xie, Bruker Optics
2:25 “Time-domain NMR: Uses and Contributions to Process Control”
Vaughn Davis, Progression
2:50 “Recent Progress of NMR and MRI in Petroleum Exploration”
YiQiao Song, Schlumberger-Doll
3:15 Break
3:35 “Applications of Time-domain NMR to Laboratory and On-line Polymer Analysis”
Maziar Sardashti,ConocoPhillips
4:00 “Challenges in On-line Water Cut Monitoring of Heavy Oil Thermal Operations Using Low Field NMR”
Sergey Kryuchkov, University of Calgary
4:25 “Benchtop Fluoride NMR: A Rapid QC/QA Method”
Chris Borgia, Colgate-Palmolive
The Wood-Based Biorefinery in a Petroleum Depleted World
The Mid-Hudson Section of the American Chemical Society and Vassar College Announce
The Wood-Based Biorefinery in a Petroleum Depleted World
Dr. Arthur J. Stipanovic,
Professor and Chair, Department of Chemistry
State University of New York, College of Environmental Science and Forestry (SUNY-ESF)
Wednesday, November 7th, 2007
Time: 7:00 pm
Location: Mudd Chemistry Building, Third Floor
Refreshments will be served at 6:30 pm
Vassar College, Poughkeepsie, New York
Contact: Dr Joseph Tanski (jotanski@vassar.edu, 845-437-7503)
Abstract: The 21st century is envisioned to become the age of biology as renewable biomass resources replace petroleum in energy and industrial product applications. Motivated by concerns over national energy security, global CO2 reduction, a need for biodegradable products, and enhanced rural economic development, the engineering and construction of biorefineries for the manufacture of fuels, chemicals, polymeric materials and power from renewable resources is now a critical national priority. The context and intent of a biorefinery must be much more than simply replacing crude oil with renewable raw materials. A successful biorefinery must: 1) efficiently separate its raw material source into individual components, and, 2) be able to convert these components into marketplace products. The biorefinery must mirror the efficiency of today’s modern petrochemical refinery in using all components of its raw material source for the production of chemicals, fuels, and power.
Woody lignocellulosic biomass is a complex, composite material consisting of three polymers in close association: hemicellulose, cellulose, and lignin plus small amounts of low molecular weight extractives and inorganics. In this presentation, a group of synergistic biomass feedstock and biorefining technologies under development at SUNY-ESF, in collaboration with many industrial and academic partners, will be discussed including: short-rotation fast growing willow production, biodelignification, hemicellulose extraction, polymer conversion to fermentable sugars, biodegradable thermoplastics and hemicellulose-based composites.
See the Stipanovic Website at SUNY_ESF for further details…..http://www.esf.edu/chemistry/faculty/stipanov.htm
Bio: Dr. Arthur J. Stipanovic is currently Professor and Chair of the Department of Chemistry at the SUNY College of Environmental Science and Forestry (SUNY-ESF) in Syracuse , NY , and also serves as Director, Analytical and Technical Services. His research interests include biodegradable polymers from renewable resources, high-throughput analytical techniques for determining the composition of woody biomass and new processes for the wood-based biorefinery. Dr. Stipanovic received both his B.S. and Ph.D. degrees from SUNY-ESF in polymer chemistry and much of his career was spent at the Texaco R&D labs in Beacon, NY, in new technology and lubricants research. He is a past Councilor and Executive Board member of the Mid-Hudson ACS section and, more recently, has served as Chair of the Syracuse section.
Directions: Vassar College is located off Raymond Avenue in Poughkeepsie , NY. Refer to the following link for driving directions and campus map: http://www.vassar.edu/directions/. Enter the Main Entrance of the campus on Raymond Avenue and go right towards the Mudd Chemistry Building. The Security Guard at the Main Entrance will direct you to parking.